Medical Terminology Glossary
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abdomen - the area between the diaphragm and the pelvis

abdominal cavity - superior portion of the abdominopelvic cavity that contains the stomach, spleen, liver, gallbladder, pancreas, small intestine, and most of the large intestine

abdominopelvic - inferior component of the ventral body cavity that is subdivided into an upper abdominal cavity and a lower pelvic cavity

abduction - movement away from the axis or midline of the body or one of its parts

abortion - premature loss (spontaneous) or removal (induced) of an embryo or non-viable fetus; any failure in the normal process of developing or maturing

abrasion - a portion of skin that has been scraped away

abscess - a localized collection of pus and liquefied tissue in a cavity

absorption - the taking up of liquids by solids or of gases by solids or liquids; intake of fluids or other substances by cells of the skin or mucous membranes; the passage of digested foods from the gastrointestinal tract into blood or lymph

accommodation - a change in the curvature of the eye lens to adjust for vision at various distances; focusing

accretion - a mass of material that has accumulated in a space or cavity; the adhesion of parts

acetabulum - the rounded cavity on the external surface of the coxal (hip) bone that receives the head of the femur

acetylcholine - a neurotransmitter, liberated at synapses in the central and peripheral nervous systems and at neuromuscular junctions to stimulate muscle contraction

achlorhydria - absence of hydrochloric acid in the gastric juice

acidosis - a condition in which blood pH ranges from 7.35 to 6.80 or lower

acinar - flasklike

acini - masses of cells in the pancreas that secrete digestive enzymes

acoustic - pertaining to sound or the sense of hearing

acromegaly - condition caused by hyper-secretion of human growth hormone (hGH) during adulthood; characterized by thickened bones & enlargement of other tissues

acrosome - a dense granule in the head of the spermatozoon; contains enzymes that facilitate the penetration of a spermatozoon into a secondary oocyte

actin - the contractile protein that is located in the thin myofilaments of a muscle fiber (cell)

acuity - clearness or sharpness, usually of vision

acupuncture - the insertion of a needle into a tissue for the purpose of drawing fluid or relieving pain; also an ancient Chinese practice employed to cure illnesses by inserting needles into specific locations of the skin

adaptation - adjustment of the pupil of the eye to light variations; the property by which a neuron relays a decreased frequency of action potentials from a stimulus of constant size; decrease in perception of sensation with continued stimulation

adduction - movement toward the axis or midline of the body or one of its parts

adenohypophysis - the anterior portion of the pituitary gland

adenoids - the pharyngeal tonsils

adenosine triphosphate - universal energy-carrying molecule manufactured in all living cells as a means of capturing and storing energy; it consists of the purine base adenine, the sugar ribose & 3 linearly-arrayed phosphate groups

adenylate cyclase - the enzyme that converts ATP into cyclic AMP; it is located in cell membranes and is activated when messenger molecules (e.g., neurotransmitters or hormones) bind to specific molecular receptors on the cell surface

adherence - firm contact between the plasma membrane of a phagocyte and an antigen or other foreign substance

adhesion - abnormal joining of parts to each other

adipocyte - fat cell; derived from a fibroblast

adrenal cortex - the outer portion of an adrenal gland; divided into three zones, each of which has a different cellular arrangement and secretes different hormones

adrenal medulla - inner portion of an adrenal gland; consists of cells that secrete epinephrine and norepinephrine in response to stimulation of preganglionic sympathetic neurons

adrenergic fiber - a nerve fiber that when stimulated releases norepinephrine (noradrenaline) at a synapse

adrenocorticotropic hormone - hormone produced by the adenohypophysis (anterior lobe) of the pituitary gland; influences the production & secretion of certain hormones of the adrenal cortex

adventitia - the outermost covering of a structure or organ

afferent arteriole - blood vessel of a kidney (nephron) that subdivides into a capillary network called the glomerulus; there is one afferent arteriole for each glomerulus

agglutination - clumping of microorganisms or blood corpuscles; typically an antigen-antibody reaction

agglutinin - a specific principle or antibody in blood serum; capable of causing the clumping of bacteria, blood corpuscles or particles; also called an isoantibody

agglutinogen - a genetically-determined antigen located on the surface of erythrocytes; basis for ABO grouping and Rh system of blood classification; also called an isoantigen

agnosia - loss of the ability to recognize the meaning of stimuli from the various senses (visual, auditory, tactile)

agraphia - an inability to write

albinism - abnormal, nonpathological, partial or total absence of pigment in skin, hair and eyes

albumin - the most abundant (60%) & smallest plasma protein; functions primarily to regulate osmotic pressure of plasma

albuminuria - presence of albumin in the urine

aldosterone - mineralocorticoid produced by the adrenal cortex; brings about sodium and water reabsorption and potassium secretion

alimentary - pertaining to nutrition

alkaline - containing more hydroxyl ions (OH-) than hydrogen ions (H+) to produce a pH of more than 7

alkalosis - a condition in which blood pH ranges from 7.45 to 8.00 or higher

allantois - a small, vascularized membrane between the chorion and amnion of the fetus; serves as an early site for blood formation

alleles - genes that control the same inherited trait (such as height or eye color); they are located at the same position (locus) on homologous chromosomes

allergen - an antigen that evokes a hypersensitivity reaction

allergic - pertaining to or sensitive to an allergen

alveolus - a small hollow or cavity; an air sac in the lungs; milk-secreting portion of a mammary gland

Alzheimer's disease - disabling neurological disorder characterized by dysfunction and death of specific cerebral neurons; this results in widespread intellectual impairment, personality changes, and fluctuations in alertness

ambulatory - capable of walking

amenorrhea - absence of menstruation

amnesia - a lack or loss of memory

amniocentesis - removal of amniotic fluid by inserting a needle transabdominally into the amniotic cavity

amnion - innermost fetal membrane; a thin transparent sac that holds the fetus suspended in amniotic fluid; also called the bag of waters

amniotic fluid - fluid in the amniotic cavity, the space between the developing embryo (or fetus) and amnion; the fluid is produced initially as a filtrate from maternal blood and later, from fetal urine

amorphous - without definite shape or structural differentiation; pertains to solids without crystalline structure

amphiarthrosis - articulation in which the articulating bony surfaces are separated by an elastic substance to which both are attached; the mobility is slight, midway between a synarthrosis and a diarthrosis

ampulla - saclike dilation of a canal

amyotrophic - amyotrophic lateral sclerosis (ALS) - progressive neuromuscular disease characterized by spinal cord motor neuron degeneration that leads to muscular weakness; also called Lou Gehrig's disease

anabolism - synthetic energy-requiring reactions whereby small molecules are assembled into larger ones

anaerobic - not requiring molecular oxygen

analgesia - pain relief

anaphase - the third stage of mitosis in which the chromatids that have separated at the centromeres move to opposite poles of the cell

anaphylaxis - against protection; a hypersensitivity (allergic) reaction in which IgE antibodies attach to mast cells & basophils, causing them to produce mediators (e.g., histamine) leading to greater capillary permeability, smooth muscle contraction & mucus secretion

anastomosis - an end-to-end union or joining together of blood vessels, lymphatics or nerves

anatomical position - a position of the body universally used in anatomical descriptions in which the body is erect, facing the observer, the upper extremities are at the sides, the palms of the hands are facing forward, and the feet are on the floor

anatomy - the structure or study of structure of the body and the relation of its parts to each other

androgen - substance producing or stimulating male sex characteristics, e.g., the male hormone testosterone

anemia - condition of the blood in which the number of functional red blood cells or their hemoglobin content is below normal

anesthesia - total or partial loss of feeling or sensation, usually defined with respect to loss of pain sensation; may be general or local

aneuploid - a cell that has one or more chromosomes of a set added or deleted

aneurysm - a saclike enlargment of a blood vessel caused by a weakening of its wall

angina pectoris - pain in the chest related to reduced coronary circulation; it may or may not involve heart or artery disease

angiography - X-ray examination of blood vessels after injection of a radiopaque substance

angiotensin - either of two forms of a protein associated with regulation of blood pressure; angiotensin I, produced by action of renin on angiotensinogen, is converted by a plasma enzyme into angiotensin II which releases aldosterone

anion - a negatively charged ion; e.g., the chloride ion (Cl-)

ankyloglossia - tongue-tied; restriction of tongue movements by a short lingual frenulum

ankylosis - severe or complete loss of movement at a joint

anomaly - abnormality that may be a developmental (congenital) defect; a variant from the usual standard

anopsia - a defect in vision

anorexia nervosa - a chronic disorder characterized by severe self-induced weight loss, body-image and other perceptual disturbances, & physiological changes resulting from nutritional depletion

anosmia - loss of the sense of smell

antagonist - a muscle that has an action opposite that of the prime mover (agonist) and yields to the movement of the prime mover; a substance which blocks a receptor site where a specific molecule (agonist) binds

antepartum - before delivery of the child; occurring (to the mother) before childbirth

anterior - nearer to or at the front of the body; also called ventral

anti-oncogene - a gene that can cause cancer when inactivated inappropriately

antibiotic - literally, antilife; a chemical produced by a microorganism that is able to inhibit the growth of or kill other microorganisms

antibody - a protein produced by certain cells in the body in the presence of a specific antigen; the antibody combines with that antigen to neutralize, inhibit, or destroy it

anticoagulant - a substance that is able to delay, suppress, or prevent the clotting of blood

antidiuretic - substance that inhibits urine formation

antigen - any substance that when introduced into the tissues or blood induces the formation of antibodies and reacts only with its specific antibodies

antrum - any nearly closed cavity or chamber, especially one within a bone, such as a sinus

anulus fibrosus - a ring of fibrous tissue & fibrocartilage; encircles the pulpy substance (nucleus pulposus) of an intervertebral disc

anuria - a daily urine output of less than 50 ml

anus - the distal end and outlet of the rectum

aorta - the main systemic trunk of the arterial sustem of the body; emerges from the left ventricle

aperture - an opening or orifice

apex - the pointed end of a conical structure, such as the apex of the heart

apgar score - a method for assessing the overall status of an infant soon after birth; based on evaluation of heart rate, respiratory effort, muscle tone, reflex irritability, and color

aphasia - loss of ability to express oneself properly through speech, or loss of verbal communication

apnea - temporary cessation of breathing

apneustic area - portion of the respiratory center in the pons; sends stimulatory nerve impulses to the inspiratory area to activate and prolong inspiration and to inhibit expiration

apocrine gland - a type of gland in which the secretory products gather at the free end of the secreting cell and are pinched off, along with some of the cytoplasm, to become the secretion, as in the mammary glands

aponeurosis - a sheetlike tendon joining one muscle with another or with bone

appendage - a structure attached to the body

appendicitis - inflammation of the vermiform appendix

appositional growth - growth due to surface deposition of material, as in the growth in diameter of cartilage and bone; also called exogenous growth

aqueduct - a canal or passage, especially for the conduction of a liquid

aqueous humor - the watery fluid, similar in composition to cerebro-spinal fluid, that fills the anterior cavity of the eye

arachnoid - the middle of the three coverings (meninges) of the brain or spinal cord

arbor vitae - the treelike appearance of the white matter tracts of the cerebellum when seen in midsagittal secion; a series of branching ridges within the cervix of the uterus

areflexia - absence of reflexes

areola - any tiny space in a tissue; the pigmented ring around the nipple of the breast

arrector pili - smooth muscles attached to hairs; contraction pulls the hairs into a more vertical position, resulting in goose bumps

arrhythmia - irregular heart rhythm; also called dysrhythmia

arteriogram - roentgenogram of an artery after injection of a radi-opaque substance into the blood

arteriole - small, almost microscopic, artery that delivers blood to a capillary

artery - a blood vessel that carries blood away from the heart

arthritis - inflammation of a joint

arthrocentesis - insertion of a needle into a synovial (joint) cavity to remove a sample of synovial fluid, to relieve pressure, or to inject anesthetic or medication

arthrology - the study or description of joints

arthroscopy - a procedure for examining the interior of a joint, e.g., the knee, by inserting an arthroscope into a small incision; used to determine extent of damage, to remove torn cartilage, to repair cruciate ligaments, or to obtain samples for analysis

arthrosis - a joint or articulation

articular capsule - sleevelike structure around a synovial joint; composed of a fibrous capsule and a synovial membrane

articulate - to join together as a joint to permit motion between parts

articulation - a joint; a point of contact between bones, cartilage and bones, or teeth and bones

arytenoid - ladle-shaped

ascites - accumulation of serous fluid in the peritoneal cavity

aseptic - free from any infectious or septic material

asphyxia - unconsciousness due to interference with the oxygen supply of the blood

aspiration - inhalation of a foreign substance (water, food or foreign body) into the bronchial tree; drainage of a substance in or out by suction

astereognosis - inability to recognize objects or forms by touch

asthenia - lack or loss of strength; debility

astigmatism - irregularity of the lens or cornea of the eye causing an image to be out of focus and producing faulty vision

astrocyte - a neuroglial cell having a star shape; supports neurons in the brain and spinal cord and attaches neurons to blood vessels

ataxia - lack of muscular coordination; lack of precision

atelectasis - collapsed or airless state of all or part of the lung; may be acute or chronic

atherosclerosis - a process in which fatty substances are deposited in arterial walls in response to stimuli such as hypertension; following endothelial damage, white cells adhering to the walls take up cholesterol, etc., ultimately forming plaque that occludes the lumen

atresia - abnormal closure of a passage; abnormal absence of a normal body opening

atrial fibrillation - asynchronous contraction of the atria; results in the cessation of atrial pumping

atrial natriuretic factor - peptide hormone produced by the atria of the heart in response to stretching; it inhibits production of aldosterone and, thus, lowers blood pressure

atrioventricular bundle - portion of the heart's conduction system beginning at the AV node, passing through the cardiac skeleton between the atria and ventricles and into the interventricular septum where it splits into right and left bundle branches; also called bundle of His

atrium - a superior chamber of the heart

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